KMID : 0882420140870060750
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Korean Journal of Medicine 2014 Volume.87 No. 6 p.750 ~ p.755
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Metastatic Pulmonary Calcification in a Patient with Adult T-Cell Leukemia/Lymphoma
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Kim Soo-Jeong
Kang Won-Chan Kim Sun-Woong Lee Yoon-Jeong Kim Wook-Youn Kim Hyun-Jeong Lee Hong-Gi
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Abstract
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Adult T-cell leukemia/lymphoma (ATLL) is a highly aggressive disease that is geographically clustered, mirroring areas endemic for human T-cell lymphotropic virus type 1 infection. Most patients with ATLL present with aggressive manifestations such as severe hypercalcemia, lymphadenopathy, hepatosplenomegaly, and bone marrow involvement with progressive thrombocytopenia. We herein report a case of a patient with ATLL exhibiting increased uptake in both lungs as shown on a bone scan using 99mTc-methylene diphosphonate. This finding is thought to have been caused by metastatic calcification associated with ectopic parathyroid hormone production.
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KEYWORD
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Adult T cell leukemia/lymphoma, Human T lymphotropic virus type 1, Calcification, pathologic
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